Detalhe da pesquisa
1.
Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.
Cell
; 178(1): 216-228.e21, 2019 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31204103
2.
Accelerated and intensified manufacturing of an adenovirus-vectored vaccine to enable rapid outbreak response.
Biotechnol Bioeng
; 121(1): 176-191, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37747758
3.
Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B.1.1.7): an exploratory analysis of a randomised controlled trial.
Lancet
; 397(10282): 1351-1362, 2021 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33798499
4.
Manufacturing a chimpanzee adenovirus-vectored SARS-CoV-2 vaccine to meet global needs.
Biotechnol Bioeng
; 119(1): 48-58, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34585736
5.
Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial.
Lancet
; 396(10249): 467-478, 2020 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32702298
6.
Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies.
Nature
; 515(7527): 427-30, 2014 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25132548
7.
Germinal Center B Cell and T Follicular Helper Cell Responses to Viral Vector and Protein-in-Adjuvant Vaccines.
J Immunol
; 197(4): 1242-51, 2016 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27412417
8.
Demonstration of the Blood-Stage Plasmodium falciparum Controlled Human Malaria Infection Model to Assess Efficacy of the P. falciparum Apical Membrane Antigen 1 Vaccine, FMP2.1/AS01.
J Infect Dis
; 213(11): 1743-51, 2016 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26908756
9.
Neutralization of Plasmodium falciparum merozoites by antibodies against PfRH5.
J Immunol
; 192(1): 245-58, 2014 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24293631
10.
Evaluation of the efficacy of ChAd63-MVA vectored vaccines expressing circumsporozoite protein and ME-TRAP against controlled human malaria infection in malaria-naive individuals.
J Infect Dis
; 211(7): 1076-86, 2015 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25336730
11.
Increased sample volume and use of quantitative reverse-transcription PCR can improve prediction of liver-to-blood inoculum size in controlled human malaria infection studies.
Malar J
; 14: 33, 2015 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25627033
12.
Combining viral vectored and protein-in-adjuvant vaccines against the blood-stage malaria antigen AMA1: report on a phase 1a clinical trial.
Mol Ther
; 22(12): 2142-2154, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25156127
13.
Enhancing blockade of Plasmodium falciparum erythrocyte invasion: assessing combinations of antibodies against PfRH5 and other merozoite antigens.
PLoS Pathog
; 8(11): e1002991, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23144611
14.
Comparison of modeling methods to determine liver-to-blood inocula and parasite multiplication rates during controlled human malaria infection.
J Infect Dis
; 208(2): 340-5, 2013 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23570846
15.
The requirement for potent adjuvants to enhance the immunogenicity and protective efficacy of protein vaccines can be overcome by prior immunization with a recombinant adenovirus.
J Immunol
; 187(5): 2602-16, 2011 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21813775
16.
ChAd63-MVA-vectored blood-stage malaria vaccines targeting MSP1 and AMA1: assessment of efficacy against mosquito bite challenge in humans.
Mol Ther
; 20(12): 2355-68, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23089736
17.
Lyophilization to enable distribution of ChAdOx1 and ChAdOx2 adenovirus-vectored vaccines without refrigeration.
NPJ Vaccines
; 8(1): 85, 2023 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37277337
18.
STING-pathway modulation to enhance the immunogenicity of adenoviral-vectored vaccines.
Sci Rep
; 12(1): 14464, 2022 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36002507
19.
Structure of trimeric pre-fusion rabies virus glycoprotein in complex with two protective antibodies.
Cell Host Microbe
; 30(9): 1219-1230.e7, 2022 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35985336
20.
Safety and immunogenicity of a simian-adenovirus-vectored rabies vaccine: an open-label, non-randomised, dose-escalation, first-in-human, single-centre, phase 1 clinical trial.
Lancet Microbe
; 3(9): e663-e671, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35907430